Cigall Kadoch | Innovators Under 35

A major vulnerability of certain kinds of cancer is becoming clear.

Problem:
The exact biochemical mechanisms involved in many kinds of cancer remain unknown.

Solution:
While completing her PhD at Stanford, Cigall Kadoch discovered a link between a genome regulator in cells called the BAF protein complex and a rare cancer called synovial sarcoma. She and colleagues later showed that mutations of BAF are involved in at least 20 percent of human cancers, opening the door for research on drugs that target mutated BAFs.

Read the full profile in MIT Technology Review.

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