New method taps family trees for clues about conditions – Spectrum

Genetic puzzle: A new approach for finding risk variants considers data from multiple generations of a family. Hero Images/Getty Images

Asking participants in genetic databases about their family’s medical history can help researchers uncover genetic variants tied to uncommon conditions. Because people share 50 percent of their DNA with each of their parents, siblings and children, the DNA of the participants holds clues to the conditions of these relatives.

Read the full story in Spectrum.

Elizabeth Mormino | Innovators Under 35

A telltale protein seen in people’s brains before they have Alzheimer’s could offer a clue about possible treatments.

Elizabeth Mormino knows it’s too late to save her grandfather, whose Alzheimer’s disease was diagnosed a few years ago. “It’s really hard to see a familiar face go through this, knowing that there’s really no drugs that work right now,” she says. But her work may help future patients by showing an intriguing new path to treating the disease.

Read the full profile in MIT Technology Review.